P‐57 Nodular dermatofibrosis in the German shepherd dog: a retrospective study of 11 cases
Identifieur interne : 000583 ( France/Analysis ); précédent : 000582; suivant : 000584P‐57 Nodular dermatofibrosis in the German shepherd dog: a retrospective study of 11 cases
Auteurs : E. Guaguere [France] ; T. Hubert [France] ; A. Muller [France] ; J. F. Dandrifosse [France] ; A. Poujade [France] ; M. Mialot [France]Source :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
Nodular dermatofibrosis is a genetic syndrome associated with multiple collagenous nevi and renal cystadenomas or cystadenocarcinomas in the German shepherd dog. We describe a retrospective series of 11 cases of nodular dermatofibrosis in this breed. The age of diagnosis varied from 7 to 12 years. Males were overrepresented (10 cases). The chief complaint was the presence of nodules (five cases), nodules associated with poor condition (four cases) and poor condition (two cases). Lesions were present on the head (11 cases) and limbs (nine cases). In one case, nodules were observed in the oral cavity. Cutaneous lesions were characterized as multiple cutaneous or subcutaneous nodules. The nodules were firm and sometimes depilated, hyperpigmented or ulcerated. General condition was affected in six cases: anorexia (four of six), emaciation (four of six), polyuria‐polydipsia (three of six) and dehydration (three of six). Histopathological examination of nodules revealed areas of collagenous hyperplasia. Echography performed in seven cases demonstrated cystic and polylobulous structures in the kidneys. Four cases of cystadenomas and five cases of cystadenocarcinomas were confirmed by the histopathological examination of surgical or necropsy specimens from the kidneys. Euthanasia was considered either when the diagnosis was made (four of 11) or in the course of the following month (two of 11). In three cases, it was decided to remove the most damaged kidney. Two dogs survived for 9 months and another one survived over 1 year. In two cases, no surgery was performed and the dogs are still alive 12 months later. Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_57.x
Affiliations:
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Dandrifosse</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Clinique Vétérinaire, Saint‐Omer, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Blagnac, France; Laboratoire d’Anatomie Pathologique, Maisons‐Alfort</wicri:regionArea><wicri:noRegion>Maisons‐Alfort</wicri:noRegion><wicri:noRegion>Maisons‐Alfort</wicri:noRegion></affiliation></author><author><name sortKey="Poujade, A" sort="Poujade, A" uniqKey="Poujade A" first="A." last="Poujade">A. 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We describe a retrospective series of 11 cases of nodular dermatofibrosis in this breed. The age of diagnosis varied from 7 to 12 years. Males were overrepresented (10 cases). The chief complaint was the presence of nodules (five cases), nodules associated with poor condition (four cases) and poor condition (two cases). Lesions were present on the head (11 cases) and limbs (nine cases). In one case, nodules were observed in the oral cavity. Cutaneous lesions were characterized as multiple cutaneous or subcutaneous nodules. The nodules were firm and sometimes depilated, hyperpigmented or ulcerated. General condition was affected in six cases: anorexia (four of six), emaciation (four of six), polyuria‐polydipsia (three of six) and dehydration (three of six). Histopathological examination of nodules revealed areas of collagenous hyperplasia. Echography performed in seven cases demonstrated cystic and polylobulous structures in the kidneys. Four cases of cystadenomas and five cases of cystadenocarcinomas were confirmed by the histopathological examination of surgical or necropsy specimens from the kidneys. Euthanasia was considered either when the diagnosis was made (four of 11) or in the course of the following month (two of 11). In three cases, it was decided to remove the most damaged kidney. Two dogs survived for 9 months and another one survived over 1 year. In two cases, no surgery was performed and the dogs are still alive 12 months later. Funding: Self‐funded.</div></front></TEI><affiliations><list><country><li>France</li></country></list><tree><country name="France"><noRegion><name sortKey="Guaguere, E" sort="Guaguere, E" uniqKey="Guaguere E" first="E." last="Guaguere">E. Guaguere</name></noRegion><name sortKey="Dandrifosse, J F" sort="Dandrifosse, J F" uniqKey="Dandrifosse J" first="J. F." last="Dandrifosse">J. F. 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